Abnormality of hemoglobin molecules in hereditary hemolytic anemias.
نویسنده
چکیده
منابع مشابه
Red blood cell vesiculation in hereditary hemolytic anemia
Hereditary hemolytic anemia encompasses a heterogeneous group of anemias characterized by decreased red blood cell survival because of inherited membrane, enzyme, or hemoglobin disorders. Affected red blood cells are more fragile, less deformable, and more susceptible to shear stress and oxidative damage, and show increased vesiculation. Red blood cells, as essentially all cells, constitutively...
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To investigate the membrane abnormalities that may play a pathophysiologic role in several hemolytic anemias we determined the density distribution on sucrose density gradients of human red blood cell (RBC) membranes from patients with these disorders, from normal controls, and from incubated normal RBC. We analyzed the fractions for membrane-adsorbed hemoglobin (Hb), globin, and nonglobin cyto...
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Hemolysis presents as acute or chronic anemia, reticulocytosis, or jaundice. The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings. Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hered...
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the aim of this cross sectional study was to determine anemias due to deficiency of iron,vitamin B12 and folate in pregnant women,who were refered to Shahid doctor mofateh hospital in varamin.in this study hemoglobin value(<11g/dl) was used as the determinant of anemia,therefore,the study was performed on 251 pregnant women.the proportions of women having abortions and cesarean sections were 10...
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ورودعنوان ژورنال:
- Harvey lectures
دوره 49 شماره
صفحات -
تاریخ انتشار 1953